IJSR - International Journal of Scientific Research

Astha Sharma; Dr. Astha Goyal; Dr. Maheep Sinha; Dr. Bushra Fiza

Volume : VIII, Issue : VIII, August - 2019

ESTIMATION OF SERUM LIPID PROFILE IN PATIENTS WITH IMPAIRED THYROID FUNCTION

Astha Sharma, Dr. Astha Goyal, Dr. Maheep Sinha, Dr. Bushra Fiza

Abstract :

Thyroid function plays an important role in regulation of cellular activity and influences basal metabolic rate and hence general body metabolism. We carried out a study to estimate serum lipid profile in patients with impaired thyroid function. Total 150 subjects enrolled for the study were grouped on the basis of thyroid function viz. euthyroid, subclinical hypothyroidism, hypothyroidism and hyperthyroidism. Different variables of Serum Lipid Profile among the groups were compared. Serum cholesterol, TG and HDL levels were higher in the subclinical & hypothyroid group. These variables were significantly lower in the hyperthyroid group. The variation of serum TG was the most significant (F=11.37; P= 0.000). Serum VLDL levels were higher in the subclinical hypothyroid and hypothyroid group where as the levels were significantly lower in the hyperthyroid group. Serum LDL levels were as low as 62.09 ± 17.37 mg/dl in the hyperthyroid group and higher in the groups with reduced thyroid function.