ESTIMATION OF SERUM TESTOSTERONE & SHBG IN TYPE 2 DIABETES & THEIR CORRELATION WITH HbA1C & LIPID PROFILE IN TYPE 2 DIABETES CASES IN A TERTIARY CARE HOSPITAL IN KOLKATA

SOUMIKA BISWAS; LEKHA BISWAS

Volume : VIII, Issue : III, March - 2019

ESTIMATION OF SERUM TESTOSTERONE & SHBG IN TYPE 2 DIABETES & THEIR CORRELATION WITH HbA1C & LIPID PROFILE IN TYPE 2 DIABETES CASES IN A TERTIARY CARE HOSPITAL IN KOLKATA

Soumika Biswas, Lekha Biswas

Abstract :

Type 2 diabetes mellitus is one of the major causes of mortality & morbidity worldwide & studies done in recent years has showed that androgen deficiency is associated with type 2 diabetes mellitus in male population. A case control study was done in Medical College & Hospital,Kolkata,Dept. Of Biochemistry with 180 male subjects of which 100 were type 2 diabetic ,80 were age matched healthy control. The diabetic group had significantly lower level of testosterone (9.14+–3.14nmol/l) as compred to healthy control(20.61+–7.35nmol/l). Same went with SHBG where diabetic group had significanly lower value (36.4+–21.4 nmol/lit) than normal control (63.5+–18.4 nmol/lit). Fasting blood sugar & glycated Hb were negatively correlated with free testosterone and SHBG. Total cholesterol & LDL were negatively correlated with total testosterone . To precisely establish the role of testosterone in type 2 diabetes, a more elaborate study with larger study group should be done & also effect of therapeutic testosterone should be seen in large cohort.