Volume : VIII, Issue : III, March - 2019

EVALUATION OF ANALGESIC ACTIVITY OF BENAZEPRIL IN ALBINO RATS

Dr. Meenambal. S, Dr. Raadhika. K

Abstract :

Aim and Objective: To evaluate the analgesic activity of Benazepril in adult male albino rats in comparison with Aspirin.Materials and Methods:Twenty four ined adult male albino rats weighing about 150–200 gms were selected from central animal house, Madurai Medical college, Madurai. They were divided into four groups, with six rats in each. Group Iserved as control received normal feed and water. Group II served as standard received T.Aspirin– 100 mg/kg (oral). Group III was test 1 group and it receivedT. Benazepril – 5mg/kg (oral).Group IV was test 2 group and it receivedT. Benazepril – 10mg/kg (oral). The analgesic effect of benazepril was evaluated using Eddy’s hot plate method and tail–flick method and compared with the standard analgesic Aspirin.The values obtained are expressed as mean±SEM. Statistical analysis of differences between groups was carried out using one–way analysis of variance (ANOVA). Probability (P) value of <0.05 was taken as the level of statistical significance.RESULTS: Benazepril showed statistically significant analgesic activity in comparison with control group and standard group (P < 0.05).

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

EVALUATION OF ANALGESIC ACTIVITY OF BENAZEPRIL IN ALBINO RATS, Dr.MEENAMBAL. S, Dr.RAADHIKA. K INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-3 | March-2019

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