Evaluation of antidiabetic activity of aqueous extract of Coscinium fensestratum colebr stem in Alloxan induced diabetic rats

Ganesh V; Mohamed Gani A; Sarath Babu K; Sandeep VM

Volume : V, Issue : V, May - 2016

Evaluation of antidiabetic activity of aqueous extract of Coscinium fensestratum colebr stem in Alloxan induced diabetic rats

Ganesh V, Mohamed Gani A, Sarath Babu K, Sandeep Vm

Abstract :

Aims and Objectives: To evaluate the anti–diabetic activity of Coscinium fensestratum cole stem in Alloxan induced diabetic rats. Materials and Methods: Total 18 rats were selected and divided into three groups each of 6 rats. Group–I given 1% gum acacia, group–II Glibenclamide (10 mg/kg), group–III C.F stem (500 mg/kg). Blood samples were collected at different time intervals (0, 4, 6 and 8 hours) and glucose was estimated. Results: Alloxan given rats showed significant increase in glucose levels compared to control groups. Treatment with test drug significantly reduced glucose levels all the time levels compared to Alloxan group. Conclusion Coscinium fensestratum cole stem administration significantly reduced the glucose levels in Alloxan induced diabetic model.