Volume : IV, Issue : V, May - 2015

EVALUATION OF DIETARY WHITE BUTTON MUSHROOM(AGARICUS BISPORUS) AGAINST HYPERLIPIDIEMIA IN RAT MODEL

Carol Pereira

Abstract :

 To achieve weight loss and cholesterol reduction, dietary restriction remains a cornerstone of therapy. The  primary objective was to assess the effect of the dietary Mushroom powder (Agaricus bisporus) and mushroom  chitosan towards obesity. Hence the present study proposes mushroom dietary inclusions is suitable and cost effective way for the  deriving a potential obesity control strategy. This study has created evidence on the effectiveness of edible mushroom and mushroom  derived chitosan in a weight loss treatment. Six–week old male Wistar rats were divided into three groups of 10 rats each. Feeding a diet  containing a 10% powder of Agaricus bisporus fruiting bodies to hyper–cholesterolemic rats reduced plasma total cholesterol by30.18%  and dietary inclusion of chitosan also was effective in reducing it by 32–35%. Feeding mushroom fruiting body and chitosan also signifcantly reduced body weight in hypercholesterolemic rats. However, it had no adverse effects on plasma albumin,total bilirubin, direct  bilirubin, creatinin, blood urea nitrogen, uric acid, glucose, total protein, calcium, sodium, potassium,chloride, inorganic phosphate,  magnesium, or enzyme profiles(data not included). There was positive correlation(r= 0.95821; p= 0.0005< 0.05) found between body  weight and total cholesterol of the animals. The obesity induction model was successful in inducing obesity. From the “Homogeneity  of variance test” of ANOVA results we observed equal variance. During the inclusion of mushroom and chitosan in the diets,the weight  reduction was analysed by one way ANOVA and was significant(p=0.00053) @0.05 level of significance and through mean comparisons  of Tukey’s test the significant weight reduction in the obese rats by dietary supplementation of mushroom fruiting body and chitosan  was validated.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

CAROL PEREIRA EVALUATION OF DIETARY WHITE BUTTON MUSHROOM(AGARICUS BISPORUS) AGAINST HYPERLIPIDIEMIA IN RAT MODEL International Journal of Scientific Research, Vol : 4, Issue : 5 May 2015

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