EVALUATION OF ENDOSCOPIC FINDINGS & H.PYLORI INFECTION IN UPPER GASTROINTESTINAL DISORDERS  IN SOUTH MAHARASHTRA POPULATION

INGTY MOSES A.W.; GORAD KEDAR P.; SHAH SHILPA R.

Volume : V, Issue : VII, July - 2016

EVALUATION OF ENDOSCOPIC FINDINGS & H.PYLORI INFECTION IN UPPER GASTROINTESTINAL DISORDERS IN SOUTH MAHARASHTRA POPULATION

Ingty Moses A. W. , Gorad Kedar P. , Shah Shilpa R.

Abstract :

Background:Helicobacter pylori related gastritis and gastrointestinal disorders are major health ailment in developing nations. There is high morbidity and mortality ranging from chronic gastritis to gastric malignancies. Prevalence of H. pylori infection varies markedly according to regions.Aim:To study the prevalence of H. pylori gastritis in patients undergoing endoscopy and its association with the development of gastrointestinal diseases by various methods with the help of Endoscopic biopsies.Subjects and Methods:Upper G.I. Endoscopy was done in rural Maharashtra forpatients with upper G.I symptoms of dyspepsia. Punch biopsy from pylorus was taken from all these patients after proper documentation and consent.Biopsies was sent for detection of H. pylori by various methods namely Rapid Urease Test(R.U.T), histopathology, culture and microscopic staining. Results:Out of 160 cases, 108 cases i.e.67.5% was detected with H. pylori. Age group from 21–40years had the highest incidence with male predominance.Male : Female = 88 : 72 = 55 : 45%. Commonest diagnosis was Gastritis and histopathology was the method which had the most positive results 50=46.30%. Study showed that significant association of H. pylori infection with the presence of endoscopic abnormalities, peptic ulcer, gastritis and dysplasia or cancer was seen.Conclusion:The prevalence of H. pylori infection is significantly high in rural Maharashtra. Early detection and prompt treatment are essential for prevention of serious complications.