Evaluation of Fasting blood sugar levels in oral cancer, potentially malignant disorders and in patients with tobacco habit–a case control study.

Dr. Namratha. Patil

Volume : VI, Issue : I, January - 2017

Evaluation of Fasting blood sugar levels in oral cancer, potentially malignant disorders and in patients with tobacco habit–a case control study.

Dr. Namratha. Patil

Abstract :

Background: Oral cancer is one of the most common causes of death is cancer. The most common risk factor for oral cancer is tobacco. Usage of tobacco leads to changes in the oral mucosa in the form of potentially malignant disorders which further causes oral cancer. However Recent epidemiological studies have shown a strong link between diabetes and cancer.

.Hence this study was aimed to evaluate SG levels in patients with oral cancer (OC), potentially malignant disorders (PMD) and in patients with tobacco habit. Materials and Method:This case control study consisted of 80 subjects which were divided into mainly two groups; study and control groups. The study group consisted of a total of 60 patients, 20 patients in each subgroups ie, OC, PMD, patients with tobacco habits. Control group consisted of 20 healthy individuals without lesions or tobacco habits. Fasting serum samples were subjected for biochemical evaluation using BS–380 chemist autoanalyser and the results are analyzed.The values obtained were statistically analyzed using SPSS 19.0 version software. Result: There was significant increase of FBS levels in oral cancer and precancer (P<0.001). There as no change of SG in habit patients. Conclusion: There is an increased glucose levels in PMD and OC. The increased SG levels may be considered as a useful indicator for initial changes occurring in the neoplastic cells.