EVALUATION OF GLYCATED HEMOGLOBIN AS A PROGNOSTIC MARKER OF DYSLIPIDEMIA IN DIABETES MELLITUS TYPE 2 IN NORTH INDIAN POPULATION

P. Satyanarayana; Priyanka Agrahari

Volume : VIII, Issue : XI, November - 2019

EVALUATION OF GLYCATED HEMOGLOBIN AS A PROGNOSTIC MARKER OF DYSLIPIDEMIA IN DIABETES MELLITUS TYPE 2 IN NORTH INDIAN POPULATION

P. Satyanarayana, Priyanka Agrahari

Abstract :

Hyperglycemia is the main feature of diabetes mellitus type 2 which cause the non enzymatic glycation of haemoglobin and influence the lipid metabolism. In this comparative study, plasma of 150 Subjects (50–poor control (HbA1c >7%), 50–good control (HbA1c <7%) and 50–Controls) were analyzed for blood glucose and HbA1c and serum for lipid profile. A significant increase in TC, TG, VLDL–C and LDL–C concentrations were found in poor control than good control and Controls (�p�= 0.000) except HDL–C level which is not significantly increase in poor control (�p�= 0.132). In poor control HbA1c show the positive correlation with TC, TG, VLDL–C (�p�= <0.05) except HDL–C (�p�= 0.133). In good control HbA1c show significant correlation with lipid profile but less significant than poor control. This dual biomarker– HbA1c, glycemic control as well as lipid profile can be used for screening and early diagnosis of dyslipidemia.