EVALUATION OF PULMONARY FUNCTIONS IN TYPE 2 DIABETES MELLITUS AND ITS AGE AND GENDER SPECIFIC CHANGES ON POPULATION OF URBAN AND SUBURBAN AREAS OF KOLKATA: A HOSPITAL BASED STUDY

Dr. Md. Salim Uz Zaman; Dr. Md. Sadique Mallick

Volume : VII, Issue : VII, July - 2018

EVALUATION OF PULMONARY FUNCTIONS IN TYPE 2 DIABETES MELLITUS AND ITS AGE AND GENDER SPECIFIC CHANGES ON POPULATION OF URBAN AND SUBURBAN AREAS OF KOLKATA: A HOSPITAL BASED STUDY

Dr. Md. Salim Uz Zaman, Dr. Md. Sadique Mallick

Abstract :

Background: Diabetes mellitus is a metabolic disease that causes secondary changes and complications in multiple organs and pulmonary system is not an exception to this rule. It has been suggested that pulmonary dysfunctions may be one of the earliest measurable non metabolic alteration in T2DM, the potential implication of lung function status in diabetic patients demand further attention.

Aims and Objectives:Assessment of pulmonary functions in Type 2 DM and to compare(if any) according to age groups, both sexes and urban–suburban population.

Methods: A total of 60 T2DM patients of age group 35–55years and 60 age and sex matched control were included after inclusion and exclusion criteria again sub grouped into Gr.A (age 35–45yr)and Gr. B (>45yr) according to urban and suburban population.PFTand DLCO were done. The PFT parameters werecompared and correlated according to age, sex and urban–suburban population. p<0.05 was considered as significant.

Results: There was significant impairment of DLCO% (P=0.023) and DL/VA%(P=0.001) in Gr.Bage>45years) and also negative correlation of DLCO%(r=─0.377) and DL/VA%(r=─0.475) with age. But changes in urban patients were insignificant in relation to suburban.

Conclusions: Age and gender specific impairment of pulmonary function and diffusion capacity in T2DM when compared with their matched control but no significant changes when it is compared between cases from urban and suburban populations.