Experimental Evaluation of  Hypoglycaemic Activity of A Compound  Herbal Plant Formulation Against Acute  Hyperglycaemic Condition

Dwivedi; K.n.; Misra S.

Volume : II, Issue : IX, September - 2013

Experimental Evaluation of Hypoglycaemic Activity of A Compound Herbal Plant Formulation Against Acute Hyperglycaemic Condition

Dwivedi, K. N. , Misra S.

Abstract :

Though Ayurvedic medicinal plants are being internally administered since thousand of years, it is a scientific approach to investigate them through experimental models in order to evaluate their efficacy more accurately as well as to detect any possible toxicity. Present study is aimed to evaluate the hypoglycaemic effect of an Ayurvedic compound drug formulation consisting of medicinal plants / parts of the plants by virtue of their actions and properties are being used traditionally since ancient era for the treatment of Madhumeha (Diabetes mellitus), Viz – Heartwood of Vijaysar (Pterocarpus marsupium)(1,2,3) Fruits of Karela (Momordica charantia)(4), Seeds of Jambu (Eugenia jambolana)(5), Leaves of Tejpatra (Cinnamomum tamala)(6), Seeds of Methica (Trigonella foenum graceum)(7), Rhizomes of Kutaki (Picrorrhiza kurroa)(8), Leaves of Nimba (Melia azadirachta)(9), Leaves of Gudmar (Gymnema sylvestre)(10) and leaves of Tulsi (Ocimum sanctum). It would be of interest to investigate the effect of the aforesaid medicinal plants in a combined form against the Alloxan induced, Hydrocortisone induced hyperglycaemic responses in albino rats. We thought to combine these drugs in the form of a single formulation and evaluate its efficacy against P. marsupium (standard drug) whose anti–diabetic property is mentioned by many authors. (1)