Experiments in Raman Spectroscopy  on Hair Follicles from Females with  Androgenetic Alopecia

Orasan Meda Sandra; Dr. Coneac Andrei; Dr. Orasan Remus Ioan

Volume : II, Issue : VIII, August - 2013

Experiments in Raman Spectroscopy on Hair Follicles from Females with Androgenetic Alopecia

Orasan Meda Sandra, Dr. Coneac Andrei, Dr. Orasan Remus Ioan

Abstract :

Androgenetic alopecia in women is a frequent dermatological disease, characterized by shortening of anagen, hair thinning and hair loss. Although the chemical structure of untreated hair from normal patients has been intensively studied, the hair structure in patients with alopecia or other hair pathology has not been well described in literature or studied in detail. Our preliminary study investigated the potential of Raman micro-spectroscopy (RMS) in hair analysis, its capacity to point out differences between spectral footprints to discriminate the composition of hair follicles from various regions of the scalp. The spectral images were captured by Raman micro-spectroscopy, Bruker Sentera type The comparison of Raman spectra of hair follicles in the occipital and frontal areas showed a similar footprint. The data obtained do not sustain the hypothesis that besides generating a physical change of the hair follicle�s dimensions, the miniaturization process could also involve structural changes of the hair.