Volume : V, Issue : IV, April - 2016

Exploration of Hepatoprotective Activity of Aqueous Extract of Solanum nigrum

Dr. Yogesh Kumar Goyal, Dr. Anupam Sharma

Abstract :

 Aim To explore the hepatoprotective potential of Solanum nigrum. Materials and Methods Albino Wistar rats weighing 150–200g of either sex were divided into six groups of six animals each. Group I was given normal saline, group II carbon tetrachloride(CCl4), group III Liv.52 syrup for twenty days followed by CCl4, group IV, V & VI received aqueous extract of S. nigrum (1ml/100g twice daily) orally for 10, 20 & 30 days respectively followed by CCl4 administration. Blood was collected from anaesthetized animals. Alanine transaminase (ALT), Alkaline phosphatase (ALP) & Total bilirubin were estimated. Results ALT, ALP & Total bilirubin levels were significantly increased in CCl4 treated group while S. nigrum displayed significant reduction in rise in these parameters in group IV, V and VI. Conclusion It can be concluded from the present study that S. nigrum extracts are potent hepatoprotective agent.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr. Yogesh Kumar Goyal, Dr. Anupam Sharma Exploration of Hepatoprotective Activity of Aqueous Extract of Solanum nigrum International Journal of Scientific Research, Vol : 5, Issue : 4 APRIL 2016

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