Extraintestinal Pathogenic Escherichia Coli  (ExPEC): An Emerging but Less–Appreciated  Health Threat

Dr. Bhargav N Patel; Dr. Hemali Parmar; Dr.Ullas Machhar; Dr. Mala Sinha; Dr. Hitesh Shingala

Volume : II, Issue : VI, June - 2013

Extraintestinal Pathogenic Escherichia Coli (ExPEC): An Emerging but Less–Appreciated Health Threat

Dr. Bhargav N Patel, Dr. Hemali Parmar, Dr. Ullas Machhar, Dr. Mala Sinha, Dr. Hitesh Shingala

Abstract :

Infections due to Extraintestinal pathogenic Escherichia coli (ExPEC) represent a major but little-appreciated health threat. This study was conducted in the department of Microbiology, of Guru Gobind Singh Hospital, Jamnagar from January 2012 to May 2012. A total of 100 E. coli isolates from various extraintestinal infections were studied for the antimicrobial sensitivity pattern. Out of these 100, 58 were isolated from urine, 29 were from pus, 5 from blood. The analysis of drug resistance pattern shows that maximum number (90.00%) were resistant to Cefotaxime and least (2.00%) were resistant to Gatifloxacin followed by (23.00%) to Chloramphenicol & (29.00%) to Amikacin. This study demonstrates that antimicrobial resistance is on a rise among E. coli strains that cause extra-intestinal infections. Therefore, the correct detection of antimicrobial resistance is important. Judicious use of the antibiotics and good antibiotic policy are needed to limit the emergence and spread resistance in bacteria.