Functional outcome and results of Platelet rich plasma (PRP) in Treatment of Delayed Union

Dr Deepak Chaudhary; Dr Kumar Rohit; Dr Rajeshwar Kalla

Volume : V, Issue : I, January - 2016

Functional outcome and results of Platelet rich plasma (PRP) in Treatment of Delayed Union

Dr Deepak Chaudhary, Dr Kumar Rohit, Dr Rajeshwar Kalla

Abstract :

Objective: To assess functional outcome & results of injection of platelet rich plasma (PRP) in delayed union. Design: Prospective clinical study with 12 months of follow–up. Methods: Clinically proven six patients of delayed union participating in study included in study according to inclusion and exclusion criteria on OPD basis after getting written and informed consent , treated by 6 mL of autologous PRP injection thrice weekly for 4 weeks by single author*, evaluation done clinically as well as radiologically (at baseline, 1 month , 3 months, 6 month and 12 month interval). Results: The median follow–up period was 10 months (range 8–12 months) .The fractures of five patients (83.3%) achieved union at median 12 weeks (range 8–20 weeks). There was non–union of the fractures of 1 patient (16.6%), grafting and revision surgery was done in this patient. Conclusions: Thrice weekly injection of 6 ml of autologous PRP for 4 weeks is a safe and effective mean of treatment of delayed union. But to establish PRP as a definitive treatment modality larger studies with longer duration needed in future.