Granulosa Cell Tumor: A Clinicopathological Study in a tertiary hospital in South India

Dr. N. Jeyalakshmidevi; Dr. A.V.Shanti

Volume : VII, Issue : I, January - 2018

Granulosa Cell Tumor: A Clinicopathological Study in a tertiary hospital in South India

Dr. N. Jeyalakshmidevi, Dr. A. V. Shanti

Abstract :

Ovarian malignancies are the second most common malignancies( 5–6%) of the female genital tract .and Granulosa cell tumors (GCT) are the most common Sex cord stromal tumors .

The aim is based on clinico–pathological correlations of GCTcases with the Stage of the disease as per FIGO classification, to analyse various histo–morphological patterns and to highlight the utilitarian value of Immuno histochemistry .

There were 475 ovarian Neoplasms and 165 were malignant. 30 of them were GCTs (18.8 %). 23 patients (76.6%) had stage I, ( 56.6% had stage Ia, 6.6% had stage Ib , 13.3% had

stage Ic )and 23.3%had stage IIIc . Patients with early stages had well differentiated GCT and late stages were poorly differentiated. Patients with Stage I had a mean survival of 11.2 months and Stage III had a mean survival of 8.2 months.