IJSR - International Journal of Scientific Research

Dr Aarti P Pachrupe; Dr Varsha M Dhume; Dr Vikas Kavishwar

Volume : VII, Issue : VII, July - 2018

Grave's disease: Study of Clinical presentation, Hormonal, Biochemical and Radiological investigations along with cytological parameters

Dr Aarti P Pachrupe, Dr Varsha M Dhume, Dr Vikas Kavishwar

Abstract :

Grave’s disease accounts for 60–80% cases of thyrotoxicosis. Diagnosis of Grave’s Disease is based on clinical findings, thyroid function tests, USG, radioactive iodine thyroid scan and presence of anti–thyroidal antibodies. Fine needle aspiration cytology of thyroid is necessary in selected cases. We studied cytological findings in 25 cases ofGraves’ disease, where FNAC was indicated because of nodularity or cold areas on scan. All cases had elevated serum T3, T4 with high anti–TPO titers seen in majority of cases.Fire flares and lacy cytoplasm were significant cytomorphological features. Combined evaluation of clinical presentation, hormonal status, anti–thyroid antibodies and RAIU scans along with cytological parameters can correctly interpret Grave’s disease.