Histochemical Study of Mucin in the Adenomatic Transformation of Barrett's Esophagus in Human Esophageal Epithelium

Nithya Regupathi; Halagowder Devaraj

Volume : III, Issue : VII, July - 2014

Histochemical Study of Mucin in the Adenomatic Transformation of Barrett's Esophagus in Human Esophageal Epithelium

Nithya Regupathi, Halagowder Devaraj

Abstract :

Barrett�s esophagus (BE) is an early stage and predictive marker in the progression of esophageal adenocarcinoma (EAC). The prevalence and risk factors of BE and its complications are thought to be infrequent in India. There is a need for more endoscopic and histological studies on the diagnosis of BE. Mucin secretions in BE excogitate the functional state of the mucosa in human esophageal epithelium. Hence, the present study was performed to understand the mucin histochemistry using Alcian blue (AB) and Periodic Acid Schiff (PAS) staining in the progressive stages of Barrett�s adenocarcinoma.