Volume : VI, Issue : III, March - 2017

HISTOPATHOLOGICAL ANALYSIS OF HODGKIN’S LYMPHOMAS WITH SPECIAL REFERENCE TO EPSTEIN –BARR VIRUS

Dr. V. Premalatha, Dr. K. Viswanathan

Abstract :

 Abstract:            Introduction Epstein–Barr Virus(EBV) is a herpes virus and EBV positive tumour cells express latent memane protein–1(LMP–1), a protein encoded by EBV genome that has transforming activity.EBV virus infects B–lymphocytes, which will emerge as lymphomas Aim : To demonstrate EBV antigen in tissue sections of Hodgkin’s  lymphomas (HL) by immunohistochemistry (IHC)  and to   investigate the relationship between EBV associated HL in view of age, sex, site and subtype   Material And Methods:  39 cases of Hodgkin’s lymphomas were taken  for histopathological examination & IHC marker LMP–1 study. Conclusion:. LMP–1 expression is more common in males,mixed cellularity subtype, age > 45 years and in cervical nodes.  

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr.V.Premalatha, Dr.K.Viswanathan, HISTOPATHOLOGICAL ANALYSIS OF HODGKIN¥S LYMPHOMAS WITH SPECIAL REFERENCE TO EPSTEIN –BARR VIRUS, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | ISSUE-3 | MARCH‾2017

Number of Downloads : 274

References :