Histopathological lesions in Transrectal ultrasound guided biopsies of Prostate in patients with raised serum Prostate specific antigen.

Dr.Prabhat Sharma; Dr. Meena M. patel; Dr. Abhishek Raval

Volume : III, Issue : XI, November - 2014

Histopathological lesions in Transrectal ultrasound guided biopsies of Prostate in patients with raised serum Prostate specific antigen.

Dr. Prabhat Sharma, Dr. Meena M. Patel, Dr. Abhishek Raval

Abstract :

Introduction: Carcinoma of Prostate is one of the common tumors of old age in men. With digital rectal examination (DRE), Prostate specific antigen (PSA) and Transrectal ultrasound (TRUS)–guided needle biopsies of prostate are considered the gold standard for the diagnosis of the Prostatic cancer. Objectives: To determine the spectrum of Pathological lesions in TRUS–guided needle biopsies of Prostate in men with increased serum Prostatic specific antigen (PSA) levels (≥4 ng/ml) with or without symptoms of Prostatism. Patients and methods: A Retrospective study carried out at the Department of Histopathology, B.J.M.C and Civil hospital, Ahmedabad from January 2013 to November 2013. The study includes 108 cases between 50 to 76 years of age group. Serum PSA level and Histopathology of Prostatic biopsy was done and correlate. Results: In present study ,out of 108 cases, 60 (55.6%) cases showed Benign lesions with mean age 57.7 �4.86. and 48 (44.4%), Malignant with mean age 65.70 � 5.64.The mean serum PSA value was 13.36 � 8.6 ng /ml. Conclusions: In present study, Elevated level more than 4.0 ng /ml with TURS guided needle biopsy is most useful and accurate diagnostic method for Prostate.