Hypolipidemic effect of Fenugreek and Turmeric on the lipid profile: A double blind, placebo controlled randomized trial

Dr Ashok Kumar Mishra; Dr Salil Kumar Srivastava; Dr Bhupinder Kaur Anand; Col (Retd) Dr. M. Azam

Volume : V, Issue : VI, June - 2016

Hypolipidemic effect of Fenugreek and Turmeric on the lipid profile: A double blind, placebo controlled randomized trial

Dr Ashok Kumar Mishra, Dr Salil Kumar Srivastava, Dr Bhupinder Kaur Anand, Col Retd Dr. M. Azam

Abstract :

 Objective: To study the effect of Fenugreek and Turmeric on the lipid profile on hyperlipidemic patients. Methods: This was a randomized controlled trial conducted among the patients of dyslipedemia. Subjects were selected from outdoor clinic. Subjects (30–60 yrs) with BMI>25, total Cholesterol > 200 mg/dl and / or triglycerides >150 mg/dl who had not been treated for dyslipedemia were included in the study. 1.6g aqueous extract (25 grams of Fenugreek powder) was given orally per day in the form of capsules. 1.4g aqueous extract (twelve grams of Turmeric) was given. Four capsules of 500 mg in two divided dose per day till two months. Placebo was given in the same way which was an inert material in nature to make the study double blind. Same color of capsule was used for all the three groups. Results: Administration of Fenugreek and Turmeric has significantly lowered the levels of Total cholesterol; LDL cholesterol and triglyceride at 45 and 75 days. The HDL cholesterol levels showed slight increase at 45 days in both Fenugreek and Turmeric groups. The effects of Fenugreek and Turmeric were variable in lowering the total Cholesterol, Triglycerides and LDL. In terms of increasing HDL and decreasing VLDL, the effects of Fenugreek and Turmeric were comparable to each other. In the Placebo group, there was a mild reduction in the levels of cholesterol, triglycerides and LDL levels. Conclusion: We found no significant difference their activities between each others, they can also be given in combinations with each other.