Volume : VIII, Issue : VII, July - 2019

Hypothyroidism presenting as reversible renal impairment

Dr Aravind Raj, Dr Suresh Kanna

Abstract :

We describe an interesting case of reversible renal impairment secondary to hypothyroidism. A 54–year–old female came with the complaints of b/l leg swelling for 2 weeks which was gradual in onset . H/o peri–orbital and facial oedema (+). Two–week history of swelling was preceded by several months of vague constitutional symptoms including tiredness, lethargy, and leg muscle cramping. She was found to have hypothyroidism, and thyroid hormone replacement therapy (THRT) was started which resulted in reversal of the renal dysfunction. There was marked improvement in estimated glomerular filtration rate. Several studies have described the pathophysiology of diminished renal function in hypothyroidism. Few studies or case reports have shown total amelioration of renal impairment as seen in our patient. The etiology is presumed to be multifactorial, in which hemodynamic effects and a direct effect of thyroid hormone on the kidney play an important role. We suggest that patients with renal impairment of unknown cause have thyroid function tests undertaken as part of routine investigation.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

HYPOTHYROIDISM PRESENTING AS REVERSIBLE RENAL IMPAIRMENT, Dr Aravind Raj, Dr Suresh Kanna INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-7 | July-2019

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