Volume : III, Issue : VII, July - 2014

Immuno Modulatory Potential of Bone Marrow Derived Mesenchymal Cells Against a Biological Graft

Dr Remyav, Naveen Kumar

Abstract :

In the present study bone marrow derived mesenchymal cells of rat (R-BMSCs) were seeded over fish swim bladder (FSB) matrix. This cell- matrix construct was implanted in 20×20mm2 size full thickness skin defect created on rat model. Humoral and cell mediated immune response against this biological graft was tested through ELISA and Lymphocyte Stimulation Test (LST) respectively. Results were compared with that of control model, where fish swim bladder alone, without R-BMCs was used as biological graft. The immune response elicited by test model was significantly (P<0.05) negligible when compared to control model, emphasizing the immuno modulatory potential of bone marrow derived mesenchymal cells.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr RemyaV, Naveen Kumar Immuno Modulatory Potential of Bone Marrow Derived Mesenchymal Cells Against a Biological Graft International Journal of Scientific Research, Vol : 3, Issue : 7 July 2014

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