IMMUNOPATHOLOGICAL CHANGES INDUCED BY SENSITIZED SPLEENIC CELLS IN SPLEEN OF W.L.H CHICKS  DURING EXPERIMENTAL ASCARIDIASIS

Mamta Rani; Malti; L. S. Gautam; Indu Yadav

Volume : V, Issue : IX, September - 2016

IMMUNOPATHOLOGICAL CHANGES INDUCED BY SENSITIZED SPLEENIC CELLS IN SPLEEN OF W.L.H CHICKS DURING EXPERIMENTAL ASCARIDIASIS

Mamta Rani, Malti, L. S. Gautam, Indu Yadav

Abstract :

Newly hatched WLH chicks were infected by Ascaridia galli eggs with 1500 eggs and 3000 eggs subsequently immunized with spleenic cells. After 15 and 30 days of post infection spleen showed various pathological changes with high dose of infection. After 15 days of PI the T.S passing through the spleen revealed mild depletion of lymphocytes, distinct secondary module and parallel non– inflammatory edema in red pulp .The reticular tissues revealed prominent dowdy swelling. The red and white pulp area showed depletion of lymphocytes. Venous sinuses were highly dilated .After 30 days of PI the capsular wall was thickened with wavy outline. White pulp revealed dilated spleenic blood vessel and depletion of lymphocytes and capsular walls was ruptured at various places and white pulp showed inflammatory edema while in the immunized chicks the spleen not showed changes.