Volume : II, Issue : X, October - 2013

In Vitro Study of the Litholytic Effects of Selected Food Extracts on Renal Stones

Dr M. Rajeswari, Sudha Rani Ks

Abstract :

Present study investigated the in vitro renal calculi dissolving activity of plant foods of Indian origin namely Papaya fruit, Coconut flower, Drumstick leaves, Flax seeds and Radish. Renal stones were treated with plant extracts and kept in constant stirring conditions for a period of 6 weeks. NaCl (9 g/L) solution was used as control. At the end of every two weeks, the stone was removed from the experimental medium and weighted after a 5 hour drying period at 100°C.The parameters measured were reduction in stone weight after 6 weeks, % of weight reduction and dissolution rate. All the food extracts were found to reduce the weight of the stones after 6 weeks. Drumstick leaves extract was found to cause highest solubility (39.39%) in the stone which is higher than the control (26.72%) followed by coconut flower (25.42%) and papaya fruit (24.54%). In general, solubility of stone and dissolution rate (mg/24 hours) was more in 1st 2 week period as compared to 2nd and 3rd 2 week period for all the extracts except for flax seeds and radish. These results provide a baseline data for the use of food extracts as potential agents in the treatment of renal stones.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr M. Rajeswari, Sudha Rani KS / In Vitro Study of the Litholytic Effects of Selected Food Extracts on Renal Stones / International Journal of Scientific Research, Vol.2, Issue.10 October 2013

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