In–silico approach to Contemporary Drug Discovery and Development process

Volume : IV, Issue : I, January - 2015

Bhagavati Parekh

Drug research and development (R & D) is a comprehensive, expensive, and time-consuming practice, and it is

full of risk throughout the process. It contains a number of stages, each having its own importance and implications

on the successful formation of any drug. In the last four decades, computational technologies for drug Research and Development have

advanced very quickly, particularly in last few years with the unprecedented development of various disciplines which jointly provide sound

and commendable platform for naval drug discovery. There are numerous CADD software, applicable at each stage of Drug Discovert to

facilitate and accelerate the process in more efficient manner. Together with the increasing capacity for biological screening and chemical

synthesis, more demands for large quantities of early information on Absorption, Distribution, Metabolism and Excretion are rising. The

highly increasing need for the medium and high throughput in-vitro screens is the outcome of this changing requirement.