Incidence of Bactibilia in Uncomplicated Cholelithiasis and its Association with Post Operative Surgical Site Infections

Mangtani Jitendra K.; Bhat Mahakshit; Rawat Karan R.; Jain Ankita; Khan Shahzad; Dangayach Krishan K.

Volume : VI, Issue : V, May - 2017

Incidence of Bactibilia in Uncomplicated Cholelithiasis and its Association with Post Operative Surgical Site Infections

Mangtani Jitendra K. , Bhat Mahakshit, Rawat Karan R. , Jain Ankita, Khan Shahzad, Dangayach Krishan K.

Abstract :

Introduction: Gallstone disease is a common cause of surgical intervention, with an estimated prevalance of 6.2% in Indian population. Cholecystectomy is associated with multiple complications with SSI being one of the commonest. We performed this study with the aim of establishing the causative association between bactibilia and SSI. Aims And Obectives: Our aim was to determine the incidence of bactibilia and evaluate its role in post–operative surgical site infections. Further our objectives were to know the bacteriology of bile, antibiotic sensitivity profile of organisms isolated in bile, and comparison of incidence of bactibilia in normal bile and in patients with cholelithiasis Materials and methods: This prospective study was performed by obtaining samples of bile from 100 patients who underwent cholecystectomy. In the control group we obtained bile samples from 50 patients who underwent laparotomy for causes other than diseases of the biliary tree and peritonitis. The samples obtained were cultured for anaerobic organisms and an antibiotic sensitivity profile was obtained. Results: The most common organism cultured in bile was Escherichia coli in 10 cases (66.67%) followed by Pseudomonas aeruginosa in 3 patients (20%) and one patient each with Klebsiella pneumoniae and polymicrobial flora. In the control group bile was sterile in 96% of the cases with bactibilia present in only 2(4%) cases. The E. Coli cultured was sensitive to amikacin in 100% of the cases All the cultures of Pseudomonas aeruginosa were sensitive for amikacin and colistin The Klebsiella pneumoniae cultured from the bile in the single case was sensitive only to imipenem and gentamycin. Only three patients in the study group developed surgical site infections.. The organisms cultured were E. Coli, Staphyloccus aureus and Methicillin resistant Staphyloccus aureus (MRSA). No correlation was observed between bactibilia and incidence of surgical site infections.