Volume : VIII, Issue : V, May - 2019

Intra–operative extra–corporeal radiation: a limb sparing option in bone tumors

Dr Wagh Mira Sudam, Dr Bhaskar Subin Sugath

Abstract :

Background: Delivery of lethal dose radiation to resected tumor beå bone, and reimplantion of the resultant dead autogenous graft, is an option for limb preservation. We report an analysis of patients treated likewise. Methods: This is an analysis of 25 patients from a prospectively maintained database; who underwent extra–corporal radiation therapy between March 2012 and December 2015. Patients were evaluated for complications, delay in adjuvant therapy, bone union, recurrences, functional outcome and deaths. Results: The median age of patients was 12 years. 18(72%) had osteosarcoma, 6(24%) had Ewings sarcoma and 1(4%) patient had adamantinoma. The involved bone was femur in 12, tibia in 11, radius in 1 and humerus in 1 patient. 6 patients had complications. Adjuvant chemotherapy was started within 3weeks of surgery in 20 out of 24 patients requiring adjuvant. There were 5(20%) recurrences: 4 distant and 1 local. Mean time to all recurrence was 13.8 months (3–36). 2 patients died, both due to disease progression. Most patients have a satisfactory functional outcome. Conclusion: Extracorporeal radiation therapy is an oncologically safe option for bone tumors.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

INTRA-OPERATIVE EXTRA-CORPOREAL RADIATION: A LIMB SPARING OPTION IN BONE TUMORS, Dr Wagh Mira Sudam, Dr Bhaskar Subin Sugath INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-5 | May-2019

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