Intracerebral Schwannoma: once againReport of Two Cases and Literature Review

Alqroom Y. Rami; Fayyad M. Luma; Alqurashi R. Muath; Haddad E. Sizeph; Khasawneh H. Nidal; Al Shurbaji A. Amer

Volume : VI, Issue : VI, June - 2017

Intracerebral Schwannoma: once againReport of Two Cases and Literature Review

Alqroom Y. Rami, Fayyad M. Luma, Alqurashi R. Muath, Haddad E. Sizeph, Khasawneh H. Nidal, Al Shurbaji A. Amer

Abstract :

Rationale: Schwannoma is a benign tumor that arises from Schwann cells of the peripheral nerve sheath, and is a common tumor of the cranial nerves. Intra–parenchymal schwannomas not related to cranial nerves are very rare. To our knowledge, about 70 cases have been reported so far since the first case reported by Gibson et al in 1966. Patient concerns: We report two cases that presented with this rare condition (Intracereal Schwannoma), presenting with long–term history of epilepsy and headache. No associated neurological deficits. Patients had an exceptionally long preoperative observational period. These are the first cases of a supratentorial intracereal schwannoma reported in Jordan, also literature review. Methods: A two female patients referred for definitive treatment of long standing history of un–controllable seizures over the last 10–years. Neuro–radiologic screening showed intracereal lesion with peri–tumoral edema. The patients underwent complete surgical excision. Histopathological and immuno–histochemical examination confirmed the diagnosis. Results: We successfully treated these patients with intracereal Schwannoma related epilepsy. They had full recovery and seizure free after 2 years. Conclusion: Intracereal schwannoma is a very rare tumor, however it should be considered in the differential diagnosis list when a well–circumscribed small nodule with typical signal and dynamic characteristics is present. The final diagnosis should be done after histopathological and immuno–histochemical examination.