Ischemia modified albumin(IMA)-a sensitive marker in the early diagnosis of Acute coronary syndrom(ACS)?

Dr. Uday B. Nayak; Dr. Lulu Cyriac; Dr. Sowmya Mathew

Volume : VII, Issue : XI, November - 2018

Ischemia modified albumin(IMA)-a sensitive marker in the early diagnosis of Acute coronary syndrom(ACS)?

Dr. Uday B. Nayak, Dr. Lulu Cyriac, Dr. Sowmya Mathew

Abstract :

Background:

Diagnosing a case of Acute Coronary Syndrome in the emergency department is quite challenging. Early diagnosis and treatment helps in reducing mortality.

Materials and methods:

A total number of 120 patients were included who came to the emergency department with symptoms suggestive of ACS. IMA was done along with the routine work up and compared with the routine cardiac markers.

Results

Mean IMA value was 88.83 + 7.575u/ml in UA group, 87.32 + 9.250u/ml in MI group and 55.96 + 25.332u/ml in NICP group which showed a sensitivity of 92% and specificity of 87% compared to CKMB which was 68% sensitive and 70% specific. The positive predictive value of the test was 88% and negative predictive value was 94%. In 14 patients an early diagnosis could be made when compared with Trop–I.