Volume : V, Issue : VIII, August - 2016

ISCHEMIA MODIFIED ALBUMIN IN HYPOTHYROIDISM PATIENTS

Dr. P. T. Komala

Abstract :

 Aim: The aim of this study was to assess the study was conducted to estimate the levels of Ischemia Modified Albumin in hypothyroidism patients. Ischemia Modified Albumin (IMA) is an ischemia/reperfusion injury marker which has been considered to be formed under oxidative stress conditions. Thyroid is one of the largest endocrine gland in the body. The thyroid gland, so named by Thomas Wharton in 1965. It is larger in females than in males. The structure and function of the thyroid change in different stages of the sexual cycle in females. Its function is slightly increased during pregnancy and lactation and is decreased during menopause. Materials and methods: A cross sectional study was done with 30 newly diagnosed hypothyroid patients as cases and 30 age and sex matched healthy controls. Serum levels of IMA were estimated by colorimetric methods and thyroid profile was done by CLIA methodology. Results : Ischemia Modified Albumin levels were found to be significantly decreased in hypothyroid patients (0.18±0.01 ODU) when compared to healthy controls (0.29±0.01 ODU) (p=0.00). Conclusion: We conclude that there was decrease in IMA levels which could be due to the consequence of ischemia which is present in hypothyroidism.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr.P.T. Komala ISCHEMIA MODIFIED ALBUMIN IN HYPOTHYROIDISM PATIENTS International Journal of Scientific Research,Volume : 5 | Issue : 8 |August 2016

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