Volume : IV, Issue : IX, September - 2015

ISOLATION AND BIOACTIVITIES OF CYNODON DACTYLON : A CASE STUDY

Mrs B. Geetha

Abstract :

Medicinal plants are a source of a very rich botanical wealth. A large number of diverse types of plants grow in different parts of India. Mainly in developing countries herbal medicine is still the mainstay of about 75–80% of the whole population, for primary health care, better cultural acceptability, better compatibility with the human body and fewer side effects. Cynodon dactylon (Linn.) Pers. commonly known as “durva” of Poaceae family is a perennial creeping herb found almost all over India. It has many pharmacological activities such as diuretic, anti diabetic, anti microbial and wound heeling and many constituents like β–sitosteral, ergonosinine. A complete understanding of medicinal plants involves a number of disciplines including commerce, genetics, quality control and pharmacology. A large portion of the Indian population even today depends on the Indian system of medicine Ayurveda, ‘an ancient science of life’. The well known treatises in Ayurveda are charka samhita and Sushrutha samhita. A pharmacist is able to do chromatography and other procedures necessary for the identification and determination of purity in addition to the study of macroscopically and histological characters of the dried plant. An anticancer drug paclitaxel from taxus onifolia emerged up to the clinical trial stage with help of this method. Cynodon dactylon is commonly available grass with more medicinal uses. Five different phyto constituents were isolated from crude methanolic extract by column chromatography using ethyl acetate (0–20): n–hexane (100–80) solvent system, the Rf values of the isolated components are 0.86, 0.58, 0.48, 0.34, 0.26 respectively. These are identified and confirmed with HPTLC and TLC analysis. It can be noticed that the better anti ulcer activity in leaf extract of Cynodon dactylon than stolon extract. The methanolic extract of Bermuda grass does not show action for CNS stimulant. The remaining isolation of other constituents was going to be performed. The ulcer induced stomach tissues are allowed for histopathological studies and diuretic activity to be performed.

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Article: Download PDF   DOI : 10.36106/ijsr  

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Mrs B. GEETHA ISOLATION AND BIOACTIVITIES OF CYNODON DACTYLON : A CASE STUDY International Journal of Scientific Research, Vol : 4, Issue : 9 September 2015

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