IJSR - International Journal of Scientific Research

David Agatha; G. Sasikala; Anand B Janagond; C. P. Ramani; P. R. Thenmozhivalli

Volume : III, Issue : I, January - 2014

Isolation of Extended Spectrum Beta Lactamase Producing Enterobacteriaceae from Wound Infections in a Tertiary Care Hospital.

David Agatha, G. Sasikala, Anand B Janagond, C. P. Ramani, P. R. Thenmozhivalli

Abstract :

Wounds can be oadly categorized as having either an acute or chronic etiology. A total of 140 patients with wound infection attending Surgical, Orthopaedic and Plastic Surgery Departments in a Tertiary Care Hospital,Chennai were studied from June 2007-May 2008.Specimens obtained from patients with acute and chronic wound infection, were analysed for bacteriological profile and antimicrobial susceptibility pattern. Enterobacteriaceae isolates obtained were anaysed for ESBL production. Out of the 140 specimens collected 149 aerobic isolates and 50 anaerobic isolates were obtained. Of the 149 aerobic isolates 74 were identified as enterobacteriaceae. 30 (40.54%) of the 74 enterobacteriaceae isolates were found to be ESBL producers. 30% and 66.6% of the ESBL producers were sensitive to ciprofloxacin and amikacin respectively. All the ESBL producers (100%) were sensitive to imipenem. This study emphasizes the need for routine evaluation of ESBL producers among clinical isolates which is essential in formulating treatment guidelines and infection control measures.