Volume : IV, Issue : V, May - 2015

KINETICS AND MECHANISM OF RUTHENIUM(III) CATALYZED OXIDATION OF ETHAMBUTOL BY CHLORAMINE–B

Nanda N, Puneeth Kumar

Abstract :

 The kinetics of oxidation of Ethambutol [EMB] by Chloramine–B [Sodium N–Chlorobenzene Sulfonamide,CAB] has  been studied in HCl medium with Ru(III) as catalyst at 313 K. The oxidation follows complex kinetics, the order with  respect to [CAB], and [HCl] each being unity, fractional order with Ru(III) and inverse first–order in [EMB], the solvent isotope effect was studied using D2O. Variation of ionic strength and addition of the reaction product had no effect on the reaction rate. However, the reaction rate  increased with decrease in dielectric constant of the medium. The effect of temperatue on the oxidation rate is studied and thermodynamic  parameters for catalysed oxidation are evaluated. The observed kinetic data suggest a possibility of oxidation reaction proceeding through  a complex formation between Ru(III) and EMB which reacts with the oxidizing species derived from CAB results in the final products. The  oxidation products formed are confirmed. The rate equation is derived and a possible reaction mechanism is proposed.

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Nanda N, Puneeth Kumar KINETICS AND MECHANISM OF RUTHENIUM(III) CATALYZED OXIDATION OF ETHAMBUTOL BY CHLORAMINE–B International Journal of Scientific Research, Vol : 4, Issue : 5 May 2015

Number of Downloads : 1212

References :