Volume : III, Issue : V, May - 2014

Lead Toxicity on Kidney Antioxidant Enzymes with The Protective Role of Ginger in Male Albino Rats

Pratap Mannem

Abstract :

 The protective effect of ginger extract against nephrotoxicity induced by lead acetate was investigated in male albino rats. Seven equal groups, each of six rats were used. Lead acetate induced kidney damage was well manifested by significant decrease in renal parameters like glutathione, superoxide dismutase and catalase. The oral administration of ethanolic extracts of Zingiber officinale along with lead acetate reversed these altered parameters to normal level which indicating the nephroprotective efficacy of Zingiber officinale against lead acetate induced kidney injury. From this, we concluded the phytochemical constituents such as flavonoids, gingerols, shagogals, phytochemicals are responsible for the nephroprotective activity of Zingiber officinale. Further extensive studies are required for its potential uses in clinical practice

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

PRATAP MANNEM Lead Toxicity on Kidney Antioxidant Enzymes with The Protective Role of Ginger in Male Albino Rats International Journal of Scientific Research, Vol.III, Issue. V, May 2014

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