Volume : V, Issue : IV, April - 2016

LIPID PROFILE IN MYOCARDIAL INFARCTION CONTROVERSIES REVISITED

Dr. G. Brindha, Dr. C. Padmavathi, Dr. D. Muthukumar

Abstract :

 INTRODUCTION : Myocardial Infarction(MI) is the most common form of heart disease and the single most important cause of death in both developed and developing countries. Risk factors for MI have been extensively studied and various studies are being conducted. MI is due to irreversible necrosis of the heart muscle secondary to prolonged ischemia. AIM IF THE STUDY : The objective of this study was to evaluate the changes in different fractions of lipid profile in Indian subjects with Acute Myocardial Infarction. During tissue necrosis, acute phasic changes occur that alter the lipid profile levels. MATERIALS AND METHODS : We compared various lipid parameters like Total Cholesterol (TC), Triglycerides (TG), Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL) taken within 24 hours of admission in 25 Acute Myocardial Infarction patients with 25 healthy control subjects. RESULTS : Concentration of TC, TG and LDL were found to be significantly increased in AMI patients with a mean value 299mgs/dl, 208mgs/dl and 220 mgs/dl respectively while it was within normal limits with a mean concentration of 184mgs/dl,133mgs/dl and 120mgs/ dl in the control group. Concentration of HDL was not significantly altered in MI (37mgs/dl)when compared with control(37mgs/dl). CONCLUSION : Identification of dyslipidemia and early treatment following myocardial infarction provide potential benefits and thus reduces the morbidity and mortality of Coronary Heart Disease (CHD). Hence it is recommended that lipid profile should be assessed within 24 hours after infarction as an exact knowledge regarding baseline serum lipids can be used to guide selection of lipid lowering medications

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr.G.Brindha, Dr.C. Padmavathi, Dr.D.Muthukumar LIPID PROFILE IN MYOCARDIAL INFARCTION CONTROVERSIES REVISITED International Journal of Scientific Research, Vol : 5, Issue : 4 APRIL 2016

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