Volume : VII, Issue : I, January - 2018

Lung Function Tests in Patients of Prediabetes and Diabetes

Ishtiaq Ahmad Sofi, Suhail Ahmad Gilkar, Masood Tanvir

Abstract :

 

Background: Prediabetes is a condition where people have blood glucose levels higher than normal but not yet high enough to be diagnosed with diabetes. WHO divides prediabetes into impaired glucose tolerance (IGT) and impaired fasting glucose (IFG). Prediabetes is a common disorder in most populations1. Before people develop Type 2 diabetes, they almost always have prediabetes2. Pulmonary Function Testing (PFT) is a complete evaluation of the respiratory system including patient history, physical examination, chest x–ray examinations, arterial blood gas (ABG) analysis and spirometry. Spirometry is the recommended objective test performed to identify abnormalities in lung volumes and air flow3. Accumulating evidence suggests that there is a close relationship between impaired lung function and diabetes mellitus (DM). Population–based studies have demonstrated associations between both obstructive and restrictive lung impairment and insulin resistance or DM4, 5. A number of Asian studies have also revealed a significant association between reduced lung function and insulin resistance, metabolic syndrome and type 2 diabetes6, 7.

Aims and objectives: To assess lung function in patients of Prediabetes and diabetes by spirometry.

Materials and methods: Our study was an observational cross sectional study. 1179 apparently healthy non–smoker adult subjects underwent fasting plasma glucose (FPG) test, 2–hr oral glucose tolerance test (OGTT) and spirometry. The spirometric parameters measured were percent predicted values of FVC (forced vital capacity), FEV1 (forced expiratory volume in 1 second), and FEV1/FVC .On the basis of FPG and 2 hr. OGTT the subjects were divided into NGT (normal glucose tolerance), Prediabetes and Diabetes groups.

Results: In this study 870 (74%) subjects had NGT, 177 (15%) had prediabetes and 132 (11%) had diabetes. FVC (% pred.) and FEV1 (% pred.) were significantly lower but FEV1/FVC (% pred.) was significantly higher in prediabetes and diabetes groups as compared to NGT group.

Conclusion: Restrictive lung disease (low lung volume) was significantly associated with prediabetes and diabetes.

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Ishtiaq Ahmad Sofi, Suhail Ahmad Gilkar, Masood Tanvir, Lung Function Tests in Patients of Prediabetes and Diabetes, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-1 | January-2018


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