Volume : V, Issue : V, May - 2016

MATERNAL AND NEONATAL FACTORS CAUSING THROMBOCYTOPENIA IN NEONATES ADMITTED TO NICU DURING 20132014

Mohammed Bilal, Bharath Raj, Ashvij Shreyan

Abstract :

 Background : Thrombocytopenia is the most common hematological abnormality which is encountered in the neonatal intensive care unit (NICU). The incidence in neonates varies greatly, depending upon the population studies. According to the frequency of thrombocytopenia and its complications, this study was performed on neonates admitted to A.J Institute of Medical Sciences–NICU from August 2013–August 2014. Materials and Methods : In a retrospective study, 250 neonates who were admitted to NICU were enrolled in the study. They were categorized to three groups regarding platelet count: mild, moderate and severe thrombocytopenia. Incidence of thrombocytopenia was determined and contribution of variables such as sex, gestational age, intrauterine growth retardation, asphyxia, sepsis, necrotizing enterocolitis, blood group, placental insufficiency in Gestational Diabetes Mellitus (GDM) and hypertension (HTN) were analyzed. Results : Neonatal thrombocytopenia was found in 91(36.4%) of 250 subjects, consisted of 77.3% early onset and 22.7% late onset, which most of them had mild and moderate thrombocytopenia. Thrombocytopenia was associated with sepsis, intrauterine growth retardation sepsis, asphyxia, Gestational Diabetes Mellitus, maternal hypertension and prematurity. There was no relation between occurrence of thrombocytopenia and gender. Conclusion : The incidence of neonatal thrombocytopenia was 36.4 %. Significant maternal risk factors that lead to thrombocytopenia were Hypertension and preeclampsia, while risk factors of neonates were asphyxia, sepsis and Intra Uterine Growth Retardation.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Mohammed Bilal, Bharath Raj, Ashvij Shreyan MATERNAL AND NEONATAL FACTORS CAUSING THROMBOCYTOPENIA IN NEONATES ADMITTED TO NICU DURING 20132014 International Journal of Scientific Research, Vol : 5, Issue : 5 MAY 2016

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