IJSR - International Journal of Scientific Research

Dr. ISHAN JOSHI; Dr. AMIT SHARMA

Volume : VIII, Issue : VIII, August - 2019

MATURITY WISE (TERM/PRETERM WISE) CHANGES IN HAEMATOLOGICAL AND BIOCHEMICAL PARAMETERS BEFORE AND AFTER EXCHANGE TRANSFUSION

Dr. Ishan Joshi, Dr. Amit Sharma

Abstract :

Background: Exchange transfusion (ET) is required in hyperbilirubinemic hospitalized neonates. Aims & Objectives: 1) To determine term and preterm wise changes in haematological and biochemical parameters before and after exchange transfusion. 2) To study the effect of whole blood exchange transfusion to decrease serum bilirubin and raise haemoglobin in neonatal hyperbilirubinemia.3) To find out the underlying disease pattern of haemolytic jaundice among the study population. Materials & Methods: The study centre at SMS and associated hospitals. Blood bank is licensed and fully equipped. Fall in serum bilirubin minimum 40 cases were required as sample size of present study. Results: – In term Neonates mean Hb (g/dl) and Haematocrit values before and after exchange transfusion were highly significant whereas in Preterm it was non–significant. In term and Preterm Neonates mean Total bilirubin (mg/dl) direct bilirubin (mg/dl) values and indirect bilirubin values before and after exchange transfusion were significant.