Metastatic carcinoma to uterine cervix from breast primary - an incidental finding: a rare case report with review of literature

Narla S; Kurian A; Subramanyan A; Ramesh BVN

Volume : VII, Issue : VII, July - 2018

Metastatic carcinoma to uterine cervix from breast primary - an incidental finding: a rare case report with review of literature

Narla S, Kurian A, Subramanyan A, Ramesh Bvn

Abstract :

Involvement of uterine cervix as the exclusive site of metastasis is very unusual. Carcinoma arising from ovary, east, stomach, gallbladder, pancreas and lung has been reported to metastasize to the uterine cervix by hematogenous spread. However in majority of the cases, metastasis to cervix is from uterine malignancies. We describe a case of 40 years woman diagnosed with east carcinoma 7 years ago. She underwent chemoradiotherapy and modified radical mastectomy. Histopathology revealed infiltrating ductal carcinoma with axillary lymph node metastasis. Immunostaining with hormonal receptors was positive for Estrogen Receptor, Progesterone Receptor and negative for Her2neu. On follow up, ultrasound showed thickened endometrium. Hysterectomy was done which incidentally revealed a tiny focus of carcinoma in the cervix. Immunohistochemistry confirmed metastasis from east primary. Incidentally detected isolated metastatic carcinoma to uterine cervix from east primary though not common, must be considered in the differential diagnosis.