Volume : V, Issue : XII, December - 2016

MICROVASCULAR COMPLICATIONS IN PREDIABETES

Sreekumar, Abdul Majeed K, M. A. Andrews

Abstract :

 Background :Pre–diabetes is a condition in which the glucose levels are higher than normal but not enough for the diagnosis of diabetes mellitus.Epidemiologic evidence suggests that the complications of diabetes begin early in the progression from normal glucose tolerance to frank diabetes1.Microvascular complications start in the pre–diabetic state itself. Based on previous studies,almost 8% of individuals with pre–diabetes have detectable early diabetic retinopathy.Between 25% and 62% of patients with idiopathic peripheral neuropathy are reported to have prediabetes. Methods : We conducted an observational cross sectional study of 100 pre diabetic patients in a tertiary care centre to study the prevalence of microvascular complications in pre diabetics, to study the prevalence of microalbuminuria, retinopathy and neuropathy in prediabetics according to sex, age group and blood sugar level and to study the association between microalbuminuria, retinopathy and neuropathy in prediabetics. Results: ?e prevalence of microalbuminuria in this study was 7%, retinopathy was 4%, and neuropathy was 8% . ?e prevalence of microalbuminuria is more in impaired glucose tolerance(IGT) compared to impaired fasting glucose( IFG). When the blood sugar rises in the prediabetic range in IFG and IGT the prevalence of microalbuminuria also rises. ?e prevalence of retinopathy was also more in IGT compared to IFG . ?e prevalence was higher in those with higher blood sugar both in IFG and IGT. Out of 100 patients were studied,60% were overweight, 11%were obese, and 29% have normal body mass index(BMI). Prevalence of overweight is seen more in IGT rather than IFG . Conclusions :?e microvascular complications like neuropathy, retinopathy and microalbuminuria starts in the pre–diabetic stage itself. Prevalence of microalbuminuria, retinopathy and neuropathy was more in IGT when compared to IFG. ?ere is significant association between microalbumunuria and retinopathy in prediabetic patient

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Sreekumar, Abdul Majeed K, M.A. Andrews, MICROVASCULAR COMPLICATIONS IN PREDIABETES, International Journal of Scientific Research, Volume : 5 | Issue : 12 |December 2016

Number of Downloads : 1214

References :