Microwave assisted synthesis and antifungal activity of some substituted 3(2–furyl) pyrazoline derivatives

J.V. Phirke; Y.K.Meshram

Volume : III, Issue : XI, November - 2014

Microwave assisted synthesis and antifungal activity of some substituted 3(2–furyl) pyrazoline derivatives

J. V. Phirke, Y. K. Meshram

Abstract :

Various chalcones were synthesized from 2–furyl acetone with substituted aromatic aldehydes which in treated with phenyl hydrazine resulted in synthesis of final compounds i.e 3( furan–2–yl)–1,5–diphenyl4–5dihydro–1–Hpyrazole;5(4–chorophenyl)–3–( furan–2–yl)–1–phenyl4–5–dihydro–1–H–pyarzole;5(4–nitrophenyl)–3–( furan–2–yl)–1–phenyl4–5–dihydro–1–Hpyarzole etc.have been synthesized employing microwave technique and confirmed by suitable spectroscopic technique such as 1H NMR. The compounds have been evaluated for the antifungal activity