Volume : V, Issue : XII, December - 2016

MILTEFOSIN A NOBLE PROTECTOR

Dr. Binay Kumar

Abstract :

 Visceral Leishmaniasis (VL) is a major public health problem in India, Nepal, Bangladesh, Sudan, Europe, the Middle East, South and Central America and Brazil. Thousands of cases of KA are seen world over every year. If untreated, KA is almost always fatal as a result of intercurrent infection. The standard drug treatment for KA is pentavalent antimonial sodium antimony gluconate (SAG), to be given parenterally. Those who donot respond to SAG, in them amphotericin B desoxycholate is given again parenterally. These drugs are too toxic for the patients. Liposomal amphotericin B is effective and safe but it is very expensive. Miltefosin (Hexadecyclophosphocholine) is an oral drug that is 100% effective not only against newly diagnosed cases of KA but also against those cases who are resistant to either SAG or amphotericinB. Miltefosine has proved to be ray of hope to all those KA patients who are either new cases or resistant to SAG or AMPB

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

DR. BINAY KUMAR, MILTEFOSIN A NOBLE PROTECTOR, International Journal of Scientific Research, Volume : 5 | Issue : 12 |December 2016

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