Modulation of Serum Proteins by Methyl Parathion in the fish Labeo rohita and Cirrhinus mrigala

S. N. C. Ray; Choudhary Sharfuddin; R. C. Sinha

Volume : V, Issue : II, February - 2016

Modulation of Serum Proteins by Methyl Parathion in the fish Labeo rohita and Cirrhinus mrigala

S. N. C. Ray, Choudhary Sharfuddin, R. C. Sinha

Abstract :

The fish as an indicator species plays an important role in the monitoring of water pollution because it responds with great sensitivity to the changes in the aquatic environment. Alterations in the serum protein fractions in response to pesticidal stress (methyl parathion) were investigated in Labeo rohita and Cirrhinus mrigala in the present study. The fish serum proteins showed 5 distinct bands viz. albumin, α1, α2, β and γ. The results showed that the α1 and α2 increased exponentially till 96 h in Labeo rohita whereas γ– globulin increased in Cirrhinus mrigala suggesting that innate response was more in Labeo rohita and acquired immune response more in Cirrhinus mrigala. The results also suggested that immune response could be altered and modulated by methyl parathionwhich could be due to the direct and indirect interactions with the corresponding genes in Labeo rohita and Cirrhinus mrigala. The physiological and biochemical significance of the serum protein profile following the treatment of methyl parathion is discussed herein.