Volume : III, Issue : IX, September - 2014

Molecular Biology of Codon Usage in One–Horned Rhino (Rhinoceros unicornis L)

Supriyo Chakraborty, Arif Uddin

Abstract :

Background: This is the first report on the codon usage pattern in Indian one–horned rhino (Rhinoceros unicornis L). No literature is available on codon usage bias in Indian one–horned rhino till to date. Indian one–horned rhino is the pride of Assam, being the state animal of Assam. The phenomenon of unequal use of synonymous codons i.e. some codons are more preferred than others in genes is known as codon usage bias. Synonymous codons which vary from two to six codons encode a particular amino acid and these generally differ in the 3rd codon position. However, the usage pattern of synonymous codons differs not only among the organisms but also among the genes within an organism. The codon bias is commonly found in highly expressed genes. Result and Discussion: In this study, we analyzed the codon usage pattern in some selected nuclear genes of one–horned rhino using bioinformatics approach. We found that the overall GC% ranged from 41.3 to 57.2 % with an average of 51.46 %. The GC3 % of rhino genes ranged from 53.3 to 73.6 % with an average of 65.2 %. ENC value varied from 50 to 60 with a mean value of 55. We found a significant negative correlation of ENC with GC (r=–0.934**, p< 0.01) and ENC with GC3 (r=–0.979**, p

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

SUPRIYO CHAKRABORTY, ARIF UDDIN Molecular Biology of Codon Usage in OneHorned Rhino (Rhinoceros unicornis L) International Journal of Scientific Research, Vol : 3, Issue : 9 September 2014

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