Neurofibromatosis: A Family Case Report and Literature Review.

Dr. Anand Gupta; Dr. Mohit Kumar; Dr. Ashwani Kumar Mathur; Dr. Anshu Sharma; Dr. Aniket Kedawat

Volume : VI, Issue : V, May - 2017

Neurofibromatosis: A Family Case Report and Literature Review.

Dr. Anand Gupta, Dr. Mohit Kumar, Dr. Ashwani Kumar Mathur, Dr. Anshu Sharma, Dr. Aniket Kedawat

Abstract :

The term neurofiomatosis (NF) is used for a group of genetic disorders that primarily affect the cell growth of neural tissues. It is oadly divided into two categories: (a) von Recklinghausen�s neurofiomatosis or NF–1, (b) bilateral acoustic neuroma or NF–2. Neurofiomatosis type 1 (NF1) is the most common type of NF, and accounts for about 90% of all cases. It is one of the most frequent human genetic diseases, with a prevalence of one case in 3,000 births. The expressivity of NF1 is extremely variable, with manifestations ranging from mild lesions to several complications and functional impairment. We describe three cases of neurofiomatosis type 1 in a family. The aim of this article is to report the NF1 in a family with different manifestations and to review the literature.