NON INVASIVE COMPUTED TOMOGRAPHIC CORONARY ANGIOGRAPHY IN PATIENTS WITH SUSPECTED CORONARY ARTERY DISEASE

Dr. Ishita Luthra; Dr. Aditi Vohra; Dr. R.K. Airon; Dr. Vijay; Dr. Harneet Narula; Dr. Amit Mittal

Volume : VI, Issue : I, January - 2017

NON INVASIVE COMPUTED TOMOGRAPHIC CORONARY ANGIOGRAPHY IN PATIENTS WITH SUSPECTED CORONARY ARTERY DISEASE

Dr. Ishita Luthra, Dr. Aditi Vohra, Dr. R. K. Airon, Dr. Vijay, Dr. Harneet Narula, Dr. Amit Mittal

Abstract :

BACKGROUND– Coronary artery disease is a major cause of morbidity and mortality. CT Coronary angiography is a useful tool in evaluation of patients with suspected coronary artery disease with excellent temporal as well as spatial resolution.

AIMS & OBJECTIVES–1. Quantification of coronary calcium by MDCT and it�s implication for determining risk of cardiovascular events.

2. Detection of significant coronary stenosis (>50percent narrowing of it�s lumen).

MATERIAL AND METHODS– This study was hospital based prospective study and was performed on 30 patients with clinical features suggestive of coronary artery disease. CT Coronary angiography was performed on 64–MDCT scanner Ingenuity (Philips Medical Systems). 80 ml of non ionic contrast iohexol with concentration of 300 mg iodine/ml was given followed by 50 ml saline flush at injection rate of 5.5ml/sec into antecubital vein.

RESULTS– Out of 30 patients, 21were males and 9 were females. Sixteen patients had calcium score of 0, eight patients had a calcium score 11–100, five patients had calcium score 101–400 and one patient had calcium score of 400–800. Thirty patients had 48 lesions, RCA had 4 obstructive and 5 non–obstructive lesions, LAD had 14 obstructive and 13 non–obstructive lesions and LCx had 6 obstructive and 4 non–obstructive lesions. The CTCA had diagnostic sensitivity of 100%, positive predictive value 80% and negative predictive value was 100%. Out of 48 plaques 10 were calcified plaques, 22 non calcified plaques and 16 mixed plaques.

CONCLUSION– Contrast–enhanced 64–slice CT is a clinically robust modality that allows non–invasive visualization of coronary arteries and identification of coronary lesions with excellent accuracy. Its high diagnostic accuracy made it an excellent non–invasive diagnostic tool in work up of patients with suspected CAD.