Non Secretory Multiple Myeloma With Paraplegia–A Rare Case Report

Dr. A. Sai Chandra Niveditha; Dr. Potharlanka P B Eswari; Dr. B. Lakshmi Prasad; Dr A. Aswini kumar; Swarna Latha G

Volume : III, Issue : VI, June - 2014

Non Secretory Multiple Myeloma With Paraplegia–A Rare Case Report

Dr. A. Sai Chandra Niveditha, Dr. Potharlanka P B Eswari, Dr. B. Lakshmi Prasad, Dr A. Aswini Kumar, Swarna Latha G

Abstract :

A 42 year old lady presented to us with sudden onset flaccid paraplegia. Spinal magnetic resonance imaging showed multiple lytic and sclerotic lesions at various levels. Thorough work up for metastasis with unknown primary and skeletal survey were performed which ruled out the evidence of any primary malignancy. The bone marrow examination showed plasmacytosis , which confirmed the diagnosis of Multiple Myeloma (Non Secretory variant) . The patient was subsequently started on steroids and chemotherapy for myeloma. Non Secretory Multiple Myeloma (NSMM), is a rare variant of the classic form of MM which shows plasmacytosis & skeletal lytic lesions but no monoclonal gammopathy in serum / urine. To our best knowledge this is the first case , we are reporting from India, of NSMM with paraplegia with diffuse osteosclerosis & osteolytic lesions