OPTIMISTIC INFLUENCE OF COMMELINA BENGHALENSIS L. AND CISSUS QUADRANGULARIS L. IN ALLEVIATING PROTECTION AGAINST QUINALPHOS INDUCED NEPHROTIC DAMAGES

Dr.P. Kokilavani; Dr. S. Achiraman; Dr. P. Pandilakshmi

Volume : IV, Issue : VIII, August - 2015

OPTIMISTIC INFLUENCE OF COMMELINA BENGHALENSIS L. AND CISSUS QUADRANGULARIS L. IN ALLEVIATING PROTECTION AGAINST QUINALPHOS INDUCED NEPHROTIC DAMAGES

Dr. P. Kokilavani, Dr. S. Achiraman, Dr. P. Pandilakshmi

Abstract :

The present study investigated the protective and the curative effect of Commelina benghalensis (CBE) and Cissus quadrangularis (CQE) against quinalphos (QP) induced oxidative stress (OS) in kidney tissue. Induction of nephrotoxicity by QP was confirmed from the rise in serum urea, uric acid and creatinine. Especially, the level of creatinine was increased significantly which is a marked indicator for kidney damage.Treatment with CBE and CQE restored the level of kidney markers thereby protecting kidney damages as substantiated by histomorphological analysis.Among the two plants, CQE showed better protection compared to CBE. The findings concluded thatCBE and CQE play a significant role in protecting cell damages from OS caused by QP.