ORAL FOCAL MUCINOSIS- A LITERATURE REVIEW

KARUNYA.KRISHNAKUMAR; RAMYA RAMADOSS; SAHANAZ PRAVEEN AHMED; SUDHA GUNASEKARAN

Volume : VIII, Issue : III, March - 2019

ORAL FOCAL MUCINOSIS- A LITERATURE REVIEW

Karunya. Krishnakumar, Ramya Ramadoss, Sahanaz Praveen Ahmed, Sudha Gunasekaran

Abstract :

Oral focal mucinosis is an uncommon soft–tissue lesion of unknown cause which was first described by Tomich in 1974. Oral focal mucinosis (OFM) is a rare disease of unknown aetiology, and most commonly occurs in adult women. Commonly seen in adults during the fourth and fifth decade of life. Oral focal mucinosis appear as a nodular lesion covered with mucosa in the appearance of a round or oval shape, pink white in color, with no clinical signs and shows predilection for the mucosa overlying bone, and keratinized mucosa is involved almost exclusively. The pathogenesis of OFM is suggestive of overproduction of hyaluronic acid by fioblasts at the expense of collagen production. Histopathologically OFM is differentially diagnosed as myxoid nerve sheath tumor & odontogenic myxoma based on special stains & IHC markers OFM is diagnosed.