ORBITAL METASTASIS IN EWING'S SARCOMA: A RARE CAUSE OF PROPTOSIS

Redhu Pallavi; Yogi Veenita; Prajapati Raju; Singh O.P.

Volume : VII, Issue : XI, November - 2018

ORBITAL METASTASIS IN EWING'S SARCOMA: A RARE CAUSE OF PROPTOSIS

Redhu Pallavi, Yogi Veenita, Prajapati Raju, Singh O. P.

Abstract :

Ewing�s sarcoma is the second most common primary malignant bone tumor that typically affects diaphysis of long bones during the second decade of life. Diagnosis is often delayed due to nonspecific presentation and is frequently misdiagnosed as osteomyelitis. Metastatic disease is present in approximately 25% of patients at diagnosis. Usual sites of metastasis are lung, bone, liver and other organs (<5%) but orbital metastasis presenting as unilateral proptosis is extremely rare. We hereby present three cases of Ewing�s sarcoma with unilateral proptosis due to orbital metastasis. The first patient is 8 year old female with Ewing�s sarcoma of shaft of left femur, received neoadjuvant chemotherapy followed by radiotherapy, but developed right eye proptosis during the course of treatment. The second patient is 5 year old female with Ewing�s sarcoma of left ulnar shaft with multiple bone and lung metastasis along with orbital metastasis leading to left eye proptosis. The third patient is 22 year old male with Ewing�s sarcoma of right thigh with multiple bone and lung metastasis along with orbital metastasis leading to left eye proptosis.